Red LED Light Therapy (RLT) is the application of particular wavelengths of red and infrared light to bring about a desired healing response. RLT is also labelled “cold laser”, “low level laser” LLLT or photobiomodulation.
There are over 4000 published medical studies detailing the effect of light therapy on a multitude of conditions – ranging from osteoarthritis, inflammation, tendon lesions, nerve regeneration, peripheral neuropathy, bacterial infections, non-healing wounds, anxiety, insomnia, Alzheimer’s, Parkinson’s disease, sports performance and exercise recovery. More recently research has seen the positive influence light therapy has on the gut microbiome.
Red/Infrared Light may aid in the management of:
- Arthritis/Joint inflammation
- Chronic Muscular pain including Back /Neck /Shoulder /Knee /Elbow
- Tendonitis
- Lymphatic drainage/Oedema
- Peripheral circulation
- Non-healing ulcers/Bruising
- Wound management
- Skin aging and scarring
- Bronchial congestion
- Flu and virus recovery
- Headaches/Migraine
- Concussion
- Insomnia
- Brain fog
- Gut microbiome
- Pre exercise stimulation
- Post exercise recovery
History of technology: The healing power of light has been around since ancient times. A Nobel Prize was awarded to Niels Ryberg Finsen over 100 years ago for his advancements in the use of red light therapy in treating smallpox and lupus outbreaks in the late 1890’s.
In October 1995, sources of red light—part of the visible spectrum of light—made their space shuttle flight debut on the second U.S. Microgravity Laboratory Spacelab mission (STS-73, Columbia) as part of experiments in plant growth.
“It was here that astronauts tending the plant growth chambers noticed little scratches on their hands began to heal,” says red light therapy researcher Janis T. Eells, Ph.D., a professor in the Department of Biomedical Sciences at the University of Wisconsin-Milwaukee. “Nothing heals in space, so NASA funded many years of research with these lights for human trials.”
These studies led to the discovery that red light therapy could be used deliberately as a type of photomedicine, which is the application of light for health and healing purposes. Visible light penetrates biological tissues, such as cells, muscle tissues and nerve tissues—with red and near-infrared (NIR) light going deeper than green, blue or violet light.
“With red light therapy, you expose an area of your body to a specific wavelength of red light emitted by a device that can range in size from handheld to whole-body,” says Casey Kelley, M.D., founder and medical director of Case Integrative Health. “Essentially, the red light stimulates your cells to work at a higher level.”
Red light therapy works by activating your mitochondria, or the powerhouse of the cell, explains Dr. Kelley. With this boost to the energy center of the cell, the cells can do their jobs—such as healing and growth—more efficiently. “Think of it as your morning coffee—red light therapy helps your cells wake up and get the job done!” says Dr. Kelley.
Potential Benefits of Red Light Therapy
There are many potential uses and benefits of red light therapy.
However, according to Elaine F. Kung, M.D., founder of Future Bright Dermatology in New York and assistant clinical professor at Weill-Cornell Medical College, it’s important to keep in mind that many of the published studies using red light as therapy are often small (less than 30 people), animal or lab studies. As a result, most medical professionals agree that more quality research with more human participants is needed.
Preliminary scientific results look very promising, though. Here are some of the conditions that are showing potential for treatment with red light therapy.
Improvement for Skin and Hair Conditions
Using light to affect positive skin changes is not a new concept. In fact, dermatologists have employed various light wavelengths in treatments for over 50 years, explains Dr. Kung.
With this in mind, one of the most commonly cited benefits of red light therapy is improvements to the skin. “It has been used to address signs of aging and skin damage, such as fine lines, wrinkles and age spots by stimulating collagen production,” says Dr. Kelley.
Perhaps the most notable benefit of red light therapy is the improved quality and texture of the skin, according to Dr. Ilyas.
Here are some specifics supporting these potential applications of red light.
- Fine lines and wrinkles. A 2020 study in the Journal of Drugs in Dermatology found that light emitting diode (LED) phototherapy may be effective when it comes to treating aging skin, with red light therapy showing promise for positive skin rejuvenation effects by boosting fibroblasts—which make collagen and, in turn, gives skin its structure, strength and elasticity.
- . Light therapy has been used to treat acne for years, especially in conjunction with medications and therapies meant to enhance the light absorption, explains Dr IIyas. Accordingly, red light therapy is being explored as an acne treatment. One recent, small study showed that treating acne with red light therapy reduced mild and moderate breakouts by 36%.
- Scarring. Skin fibrosis (i.e. scarring) annually affects more than 100 million people worldwide. Though more clinical trials are needed, there is a growing body of evidence that red light therapy may help modulate key cell characteristics that contribute to scarring. In this case, red light therapy is used to reduce collagen production in scar tissue, improving or preventing thickening scars, according to Dr. Ilyas.
- Wound healing. Difficult-to-heal wounds like diabetic ulcers present a major skin treatment issue. However, Red light therapy is showing promise when used for the acceleration of healing. Researchers posit that it is once again likely the increase in cell mitochondria activity, fibroblast proliferation,and collagen production that may contribute to this potentially positive red light therapy effect.
- Hair growth. Red light therapy has been shown to reduce the effects of androgenetic alopecia, the most common form of hair loss caused by a genetic predisposition to an excessive reaction to androgens like testosterone anytime after puberty, explains Dr. Kelley. By decreasing inflammation and increasing blood flow and circulation to the scalp, it has the potential to bring more cell activity (and nutrients) to that area. Recent studies indicate that using red light therapy may promote increased hair thickness and density, but more research is needed.
Relief from Chronic Disease Symptoms/Reduction of Pain
One potential application of red light therapy is to treat chronic pain conditions, such as fibromyalgia. Recently, the FDA approved FibroLux, the first and only therapeutic laser to treat fibromyalgia pain. “When red light therapy was administered via FibroLux laser by a health care professional three times a week for a three-week period, patients experienced a marked reduction in fibromyalgia pain,” says Dr. Eells.
Red light therapy may also reduce neuropathy pain, according to recent research.
Additionally, it may mitigate the painful side effects of some cancer treatments. “For example, a phase-three clinical trial showed the benefit of red light in reducing oral mucositis [tissue swelling and irritation in the mouth] in bone marrow transplant patients through an extraoral (outside of the mouth) application of only a couple minutes,” says Dr. Eells.
Enhancement of Fat Loss
Though red light therapy is being advertised for fat and weight loss, the jury is still out on this one. However, there are a few studies showing that the application of red light may affect adipocytes (the cells that store fat).
One older study published in the journal Obesity Surgery in 2011 found that when 40 adults with excess weight were regularly exposed to red light therapy, their adipocyte cells released triglycerides, resulting in fat loss. Participants in this study lost approximately 2.1 centimeters of girth over a four-week period.
Another 2015 study of 64 women living with obesity published in Lasers in Surgery and Medicine found that red light therapy could increase fat loss when coupled with exercise. In the study, two groups worked out for 20 minutes three times per week and then received red light therapy or a placebo light therapy. Those who worked out and then had red light therapy exhibited a greater reduction in fat mass, indicating that red light therapy may improve metabolic inflexibility.
Acceleration of Sports Recovery, and Injury Prevention
“Light can speed up the respiration process in cells and increase ATP and other mechanistic factors,” says Dr. Eells. “You stimulate cellular energy, and you stimulate the body’s ability to repair.”
Because of this, red light therapy may be promising when it comes to the treatment and prevention of a range of musculoskeletal conditions, including tendonitis and carpal tunnel syndrome.
Promotion of Brain Health
Research is increasingly demonstrating the benefits of using red light therapy for dementia, stroke, depression, anxiety and other brain conditions, explains Dr. Kelley. Continued studies indicate that brain photobiomodulation therapy may enhance the metabolic capacity of neurons and stimulate anti-inflammatory and antioxidant responses, as well as neurogenesis (the formation of new neurons). This may be particularly helpful for individuals dealing with memory or mood conditions.
Red light therapy may also help patients with Parkinson’s disease manage their symptoms and sleep/wake cycles. Thanks to the minimal risk, many researchers believe that red light therapy for brain disorders will become one of the most important medical applications in the coming years and decades.
Further reference research for Red Light Therapy
- Near Infrared Light (940nm) Improves COVID Outcomes: Exciting Randomized Control Trial
Roger Seheult, MD of MedCram examines an exciting randomized control trial demonstrating the effects of near infrared light on COVID-19. https://www.youtube.com/watch?v=ZdiUnmpOgqE - Comprehensive Database of 1442 studies on Low level laser therapy (LLLT) / photobiomodulation (PBM) / red/NIR phototherapy studies – by Vladimir Heiskanen
- Low level laser therapy for osteoarthritis and rheumatoid arthritis: a meta-analysis. The Journal of Rheumatology. Aug 2000; 27(8): 1961-9. Brosseau L, Welch V, et al.
- Photobiomics’’: Can Light, Including Photobiomodulation, Alter the Microbiome?
- Incorporation of photobiomodulation therapy into a therapeutic exercise program for knee osteoarthritis: A placebo-controlled, randomized, clinical trial. 2018 Oct;50(8):819-828. de Paula Gomes CAF, et al.
- Short term efficacy of low-level laser therapy in patients with knee osteoarthritis: a randomised placebo-controlled, double-blind clinical trial. Fukuda VO1, Fukuda TY2, Guimarães M3, Shiwa S3, de Lima Bdel C3, Martins RÁ4, Casarotto RA5, Alfredo PP6, Bjordal JM7, Fucs PM8.
- Low-level laser therapy induces dose-dependent reduction of TNFalpha levels in acute inflammation. Aimbire F1, Albertini R, Pacheco MT, Castro-Faria-Neto HC, Leonardo PS, Iversen VV, Lopes-Martins RA, Bjordal JM. A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. The Australian Journal of Physiotherapy. 2003; 49(2): 107-16. Bjordal JM, Couppe C, et al.
- Protection of skeletal muscles from ischemic injury: low-level laser therapy increases antioxidant activity. Photomed Laser Surg. 2005;23:273–277. Avni D, Levkovitz S, Maltz L, Oron U.
- Effect of phototherapy on delayed onset muscle soreness. Photomedicine and Laser Surgery. 2006 Jun;24(3):377-82. Douris P, Southard V, et al.
- Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes. Lasers in Medical Science. 2014 Nov;29(6):1967-76. Antonialli FC, De Marchi T, Tomazoni SS, et al.
- Low level laser therapy before eccentric exercise reduces muscle damage markers in humans. Eur J Appl Physiol. 2010 Nov;110(4):789-96. Baroni BM, et al.
- Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Avci P, Gupta A, et al. Semin Cutan Med Surg. 2013 Mar;32(1):41-52.
- Improved cognitive function after transcranial, light-emitting diode treatments in chronic, traumatic brain injury: two case reports. Photomed Laser Surg. 2011 May;29(5):351-8. doi: 10.1089/pho.2010.2814. Epub 2010 Dec 23 Naeser MA1, Saltmarche A, Krengel MH, Hamblin MR, Knight JA.
- Red light and the sleep quality and endurance performance of Chinese female basketball players. J Athl Train. 2012 Nov-Dec;47(6):673-8. doi: 10.4085/1062-6050-47.6.08. Zhao J1, Tian Y, Nie J, Xu J, Liu D.
- Traumatic Brain Injury: A Major Medical Problem That Could Be Treated Using Transcranial, Red/Near-Infrared LED Photobiomodulation Margaret A. Naeser, PhD, LAc1,,2 and Michael R. Hamblin, PhD3,,4,,5
- Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans. Neuroscience. 2013 Jan 29;230:13-23. doi: 10.1016/j.neuroscience.2012.11.016. Epub 2012 Nov 27. Barrett DW1, Gonzalez-Lima F.
- ABC news report: Clinical trial using the red light helmet for Parkinson’s disease symptoms. By Manika Dadson Sun February 24th 2019
- Weekend Australian October 26th 2019: Parkinson’s: Let there be light. By Suvi Mahonen
- Effects of radiofrequency, electroacupuncture, and low-level laser therapy on the wrinkles and moisture content of the forehead, eyes, and cheek. Hee-Kyoung Kim, PhD, PT1 and Jung-Hyun Choi, PhD, PT2,* Pesqui Odontol Bras. 2003 Oct-Dec;17(4):307-13. Epub 2004 Apr 19.
- The influence of low-level laser therapy on biomodulation of collagen and elastic fibers. Pugliese LS1, Medrado AP, Reis SR, Andrade Zde A.
- Botulinum toxin A (BT-A) versus low-level laser therapy (LLLT) in chronic migraine treatment: a comparison. Arquivos de neuro-psiquiatria. 2018 Oct;76(10):663-667. Loeb LM, Amorim RP, et al.
- Acute Effects of Near Infrared Light Therapy on Brain State in Healthy Subjects as Quantified by qEEG Measures.
- Declining Eyesight Improved by Looking at Deep Red Light